Abbreviation
Recombinant Cynomolgus monkey TACSTD2 protein, partial (Active)
Purity
Greater than 95% as determined by SDS-PAGE.
Endotoxin
Less than 1.0 EU/ug as determined by LAL method.
Activity
Measured by its binding ability in a functional ELISA.Immobilized Macaca fascicularis TACSTD2 at 2 μg/mL can bind Anti-TACSTD2 recombinant antibody（CSB-RA023072MA1HU） The EC50 is 1.720-2.009 ng/mL.
Species
Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)
Expression Region
31-274aa
Target Protein Sequence
QDNCTCPTNKMTVCSPDGPGGRCQCRALGSGVAVDCSTLTSKCLLLKARMSAPKNARTLVRPNEHALVDNDGLYDPDCDPEGRFKARQCNQTSVCWCVNSVGVRRTDKGDLSLRCDELVRTHHILIDLRHRPTASAFNHSDLDAELRRLFRERYRLHPKFVAAVHYEQPTIQIELRQNTSQKAAGDVDIGDAAYYFERDVKGESLFQGRGGLDLRVRGEPLQVERTLIYYLDEIPPKFSMKRLT
Note: The complete
sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is
translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application,
please explicitly request the full and complete sequence of this protein before ordering.
Tag Info
C-terminal 10xHis-tagged
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Buffer
Lyophilized from a 0.2 μm filtered PBS, 6% Trehalose, pH 7.4
Storage
Store at -20°C/-81°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Lead Time
3-7 business days
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
Notes
Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Shelf Life
The shelf life is related to many factors, storage state, storage temperature and the stability of the product itself. Generally, the shelf life of lyophilized form is 6 months at -20°C/-80°C from the date of receipt.
Datasheet & COA
Please contact us to get it.
Images
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(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
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Activity
Measured by its binding ability in a functional ELISA.Immobilized Macaca fascicularis TACSTD2 at 2 μg/ml can bind Anti-TACSTD2 recombinant antibody（CSB-RA023072MA1HU） The EC50 is 1.720-2.009 ng/mL.
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TACSTD2 Recombinant Monoclonal Antibody (CSB-RA023072MA1HU) captured on Protein A Chip can bind Recombinant Cynomolgus monkey TACSTD2 protein with an affinity constant of 0.135 nM as detected by MetaSPR Assay (WeSPRTM 200).
Description
TACSTD2 functions as a cell surface marker overexpressed in numerous epithelial cancers, where it mediates intracellular calcium signaling and promotes tumor cell proliferation and metastasis. This recombinant protein spans residues 31–274, capturing the complete extracellular domain required for antibody recognition and receptor interactions, and demonstrates robust binding activity with an EC50 of 1.720–2.009 ng/mL against a validated anti-TACSTD2 antibody in functional ELISA. The quantified binding kinetics support its use in antibody development and validation workflows, including epitope mapping and affinity maturation studies targeting TACSTD2-positive tumors. Mammalian cell expression ensures native glycosylation and disulfide bond formation critical for authentic epitope presentation, while purity exceeding 95% and endotoxin levels below 1.0 EU/μg align with standards expected in cell-based assays investigating tumor cell adhesion, migration, and immune cell trafficking in cancer metastasis models.
